Antioxidant Formula Claims Info

Ingredients:(each three tablets contain)  
%Daily Value
Beta Carotene
2,500 I.U.
50%
Vitamin C
800 mg
1333%
N-acetyl--Cysteine
500 mg
*
Vitamin E (d-alpha tocopherol succinate w/ mixed tocopherols)
400 I.U.
1333%
Quercetin
200 mg
*
Circumin Standardized Extract
200 mg
*
Resveratrol (from red wine extract)
100 mg
*
Pomegranate Extract (Standardized to 40% Ellagic Acid)
100 mg
*
Niacin (from niacinamide)
100 mg
500%
Gotu Kola (Centella asiatica)
100 mg
*
Ginkgo Biloba (standarized to 24% ginkgo flavones glycosides)
100 mg
*
Korean Ginseng (standardized to 25% ginsenosides)
100 mg
*
Grape Seed Extract (standardized to 98% proanthocyanidins)  100 mg *
Green Tea Extract (standardized to 50% polyphenols)
100 mg
*
Citrus Bioflavonoids   100 mg *
L-Glutathione
60 mg
*
Vitamin D3 (as Cholecaliferol) 
400 I.U.
*
dl Methionine
60 mg
*
Bilberry Standardized Extract  50 mg  *
Zinc (monomethionate)
15 mg
100%
Co-Enzyme Q-10
30 mg
*
Alpha lipoic acid
25 mg
*
Lycopene Standardized Extract (10%)
25 mg
*
Acai Berry Powdered Extract (4:1)
25 mg
*
Manganese (as glycinate)
5 mg
250%
Lutein
5 mg
*
Folate (as folic acid)
200 mcg
50%
Selenium (from methionate)   175 mcg 250%
Chromium Nicotinate   120 mcg 100%
Vitamin B12 (as methylcobalamin & cyanocobalamin) 100 mcg 1666%
Other Ingredients:  Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Pharmaceutical Glaze
     
*Daily value not established    
     
** There is no daily value for beta-carotene
the 240% represents a daily value for vitamin A
   

Claims:

1.This supplement is an extremely potent and highly absorbable formulation that provides outstanding antioxidant protection.11,12,13

2.The amount of each ingredient was carefully selected to provide the implied benefit based upon careful scientific and clinical studies.

N-acetyl cysteine is a potent antioxidant and protects cells from the toxic effects of oxygen

Vitamin E at 400 IU/day has been shown to reduce the risk of coronary artery disease and stroke. When taken in doses of 1200-2400 IU/day it has been suggested to reduce the effects of Alzheimer's disease14,15,16,17,18

Vitamin C is an outstanding water soluble antioxidant and may reduce the risk of heart disease and certain cancers. The same is true for beta carotene and Vitamin A13,17,19,20,21,22,23,24

Selenium has been show to support the antioxidant function of glutathione S-transferase and reduce the risk of certain cancers14,25,26,27

3.The herbs gotu kola,28,29,30 ginseng31,32,33,34 and ginkgo biloba35 are excellent for maintaining general health 38,39,40 and have the potential to enhance the sense of well-being and overall memory capacity.36

4.Grape seed extract37 is an outstanding antioxidant and has been shown to be 20 times more powerful than vitamin C and 50 times as powerful as vitamin E

References:

1.Jacobson EL. Niacin deficiency and cancer in women. J Am Coll Nutr 12(4):412-416, 1993.

2.Weggemans RM, et al. Factors related to plasma folate and vitamin B12. The SENECA Study. Int J Food Sci Nutr 48(2):141-150, 1997

3.Tell GS, et al. Folate and health - new knowledge and new recommendation. Tidsskr Nor Laegeforen, 118(20):3155-3160, 1998

4.Hall J, et al. Folic acid for the prevention of congenital anomalies. Eur J Pediatr, 157(6):445-450, 1998

5.Cuskelly GJ, et al. Effect of increasing dietary folate on red-cell folate: implications for prevention of neural tube defects. Lancet, 347(9002):657-659, 1996

6.Van Allen MI, et al. Recommendations on the use of folic acid supplementation to prevent the recurrence of neural tube defects. Clinical Teratology Committee, Canadian College of Medical Geneticists. CMAJ 149(9):1239-43, 1993

7.No known author. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Morb Mortal Wkly Rep. 41(RR-14):1-7, 1992

8.Sazawal S, et al. Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind controlled trial. Pediatrics. 102(1:1):1-5, 1998

9.Eby GA. Zinc ion availability - the determinant of efficacy in zinc lozenge treatment of common colds. J Antimicrob Chemother 40(4):483-493, 1997

10.Licastro F et al. Oral zinc supplementation in Down?s syndrome subjects decreased infections and normalized some humoral and cellular immune parameters. J Intellect Disabil Res. 38(2):149-162, 1994

11.Maresh CM, et al. Dietary supplementation and improved anaerobic performance. Int J Sport Nutr 4(4):387-397, 1994

12.Suboticanec K, et al. Effects of pyridoxine and riboflavin supplementation on physical fitness in young adolescents. Int J Vitam Nutr Res. 60(1):81-88, 1990

13.Nockels CF. The role of vitamins in modulating disease resistance. Vet Clin North Am Food Anim Pract. 4(3):531-542, 1988

14.Chen H and Tappel AL. Protection of Vitamin E, Selenium, Trolox C, Ascorbic acid palmitate, Acetylcysteine, Coenzyme Q-0, Coenzyme Q-10, Beta carotene, Canthaxanthin, and (+)- Catechin against Oxidative Damage to Rat Blood and Tissues in vivo. Free Rad Biol Med 18(5): 949-953, 1995

15.Hertog MG, Feskens EJ, Hollman PC, Katan MD, Kromhout D. Dietary Antioxidant Flavonoids and Risk of Coronary Heart Disease: The Zutphen Elderly Study. Lancet. 342(8878):1007-11, 1993

16.Riemersma RA, Wood DA, Macintyre CC, Elton RA, Gey KF, Oliver MF. Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene. Lancet. 337-1-5, 1991

17.Yamori Y et al. Nutritional factors for stroke and major cardiovascular diseases: international epidemiological comparison of dietary prevention. Health Rep 6(1):22-27, 1994

18.Hallfrisch J, et al. Vitamin A and E intakes and plasma concentrations of retinol, beta-carotene, and alpha-tocopherol in men and women of the Baltimore Longitudinal Study of Aging. Am J Clin Nutr. 60(2):176-182, 1994

19.Palmer S. Diet, nutrition, and cancer. Prog Food Nutr Sci. 9(3-4):283-341, 1985

20.Hemila H. Vitamin C and common cold incidence: a review of studies with subjects under heavy physical stress. Int J Sports Med. 17(5):379-383, 1996

21.Kasa RM. Vitamin C: from scurvy to the common cold. Am J Med Technol. 49(1):23-26, 1983

22.Leibovitz B, et al. Ascorbic acid and the immune response. Adv Exp Med Biol. 135:1-25, 1981

23.Potter JD. Beta-Carotene and the role of intervention studies. Cancer Lett. 114(102):329-331, 1997

24.Mayne ST. Beta-carotene, carotenoids, and disease prevention in humans. FASEB J. 10(7):690-701, 1996

25.Ceballos-Picot I, Merad-Boudia M, Nicole A, Thevenin M, Hellier G, Legrain S, Berr C. Peripheral antioxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer?s type-place of the extracellular glutathione peroxidase. Free Radic Biol Med 20(4):579-587, 1996

26.Chang M, Burgess JR Scholz RW and Reddy CC. The induction of specific rat liver glutathione S-transferase subunits under inadequate selenium nutrition causes an increase in prostaglandin F2a formation. J Biol Chem 265:5418-5423, 1990

27.Kim YI, et al. Nutrition chemoprevention of gastrointestinal cancers: a critical review. 54(9):259-279, 1996

28.Awang, DVC. Gotu kola. Canadian Pharmaceutical Journal (Canada), 131(7): 42-46, 1998.

29.Vukovic, Laurel. The best herbs for every stage of your life. Natural Health, 27(5); 121-25, 1998

30.Goldenberg RL. Natural Ingredients (in toiletries), Drug & Cosmetic Industry. 162(2):26, 1998

31.Nishiyama N, Chu PJ, Saito H. An herbal prescription, S-113m, consisting of biota, ginseng and schizandra, improves learning performance in senescence accelerated mouse. Biological & Pharmaceutical bulletin. 19(3): 388-93, 1996.

32.Petkov, VD, Cao Y, Todorov I, Lazarova M, Getova D, Stancheva S, Alova L. Behavioral effects of stem-leaves extract from panax ginseng C.A. Meyer. Acta Physiologica et Pharmacologica Bulgarica. 18(2): 41-8, 1992

33.Lyubimov II, Borzenkov VM, Chepurnova NE, Chepurnov SA. Effect of a polysaccharide fraction of ginseng root on Learning and memory in rats (using an active escape response as an example). Neuroscience & Behavioral Physiology. 27(5):555-8, 1997

34.Petkov VD, Nosharrof AH. Effects of standardized ginseng extract on learning, memory and physical capabilities. American Journal of Chinese Medicine. 15(1-2): 19-29, 1987.

35.Wesnes KA, Faleni RA, Hefting NR, Noogsteen G, Houben JJ, Jenkins E, Jonkman JH, Leonard J, Petrini O, van Lier JJ. The cognitive, subjective, and physical effects of ginkgo biloba/panax ginseng combination in healthy volunteers with neurasthenic complaints. Psychopharmacology Bulletin. 33(4): 677-83, 1997

36.Harbige LS. Nutrition and immunity with emphasis on infection and autoimmune disease. Nutr Health. 10(4):285-312, 1996

37.Bagchi D, Garg A, Krohn RL, Bagchi M, Bagchi DJ, Balmoori J, Stohs SJ. Protective effects of ?grape seed? proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. General Pharmacology. 30:771-776, 1998

38.Duke, J. Whoops.... (home remedies for embarrassing physical problems). Natural Health. 27(2):110, 1998

39.Cates, Nancy Dodd. How you can age-proof 40+ skin. Better Nutrition. 59(10):60-64, 1997

40.Brun Eric. Cosmetics and Botanicals as We Approach the Year 2000. Drug and Cosmetic Industry. 162(2):16-21, 1998.